Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. This training position, under the direct supervision of a Cleveland Clinic Principal Investigator will provide practical training and experience in a research setting. This position is appointed through the Lerner Research Institute. The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. This program is expected to be completed within 5 years.

Our lab is seeking a highly motivated postdoctoral fellow interested in DNA repair, replication stress and cancer signaling pathways in cancer treatment. Mouse models have been developed in the lab to address the research questions. The lab employs multi-disciplinary approaches including molecular biology, cell biology, biochemistry, CRISPR gene editing, and mouse genetics to dissect these mechanisms at both cellular model and mouse model levels.

Principal Investigator: Zihua Gong, MD

Lerner Research Institute Department: Cancer Biology

Lab Research Topics:

• DNA Damage and Repair

• Replication Stress Response

• Cancer Signaling Pathway

• Cell and Molecular Biology

• For more information about the lab's research, please visit: https://www.lerner.ccf.org/cancer-biology/gong/ or contact Dr. Gong at gongz@ccf.org .

Job Responsibilities:

• Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation

• Plan, design, and conduct research experiments

• Prepare manuscripts for publication, presentation future research

• Help train and mentor junior staff

Education:

• PhD or MD/PhD required

• MD with relevant laboratory experience may substitute for PhD

Languages:

• English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status

Work Experience:

• Previous experience in a research or academic setting. Graduate student experience meets this requirement.

• Scientific writing experience

Additional Preferred Qualities:

• Candidate should act in collegial manner and contribute to a positive lab environment

• Candidate should have a background in cell and molecular biology or related fields

• Experience in cell culture and basic biochemical and molecule biology techniques is required

• Experience in mouse experiments, CRISPR and/or flow cytometry is preferred

• Candidate should have excellent communication and organization skills

Physical Requirements:

• Ability to perform work in a stationary position for extended periods

• Ability to operate a computer and other office equipment

• Ability to communicate and exchange accurate information

• Ability to distinguish color

• Manual dexterity to handle specimens and repair equipment

• Ability to lift and transport equipment or specimens weighing up to 20 pounds

• May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.

Personal Protective Equipment:

• PPE per institutional requirements; may vary by laboratory

Preferred Application Materials:

• CV

• Cover letter

• Contact information for three references

• All application materials should be submitted directly via email to Dr. Zihua Gong at gongz@ccf.org .

Keywords: Postdoc, Research, LRI

Pay Range

Minimum hourly: $0.01

Maximum hourly: $333,340.26

The pay range displayed on this job posting reflects the anticipated range for new hires. While the pay range is displayed as an hourly rate, Cleveland Clinic recruiters will clarify whether the compensation is hourly or salary. A successful candidate's actual compensation will be determined after taking factors into consideration such as the candidate's work history, experience, skill set, and education. This is not inclusive of the value of Cleveland Clinic's benefits package, which includes among other benefits, healthcare/dental/vision and retirement.

Cleveland Clinic Health System is pleased to be an equal employment employer: Women / Minorities / Veterans / Individuals with Disabilities